A flap motif in human serine hydroxymethyltransferase is important for structural stabilization, ligand binding, and control of product release. [electronic resource]
Producer: 20200310Description: 10490-10502 p. digitalISSN:- 1083-351X
- Amino Acid Motifs
- Binding Sites
- Enzyme Stability
- Glycine Hydroxymethyltransferase -- chemistry
- Humans
- Kinetics
- Ligands
- Molecular Dynamics Simulation
- Mutagenesis
- Protein Binding
- Protein Multimerization
- Protein Structure, Quaternary
- Recombinant Proteins -- biosynthesis
- Substrate Specificity
- Tetrahydrofolates -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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