Endothelin-1 inhibits size dependent lymphatic clearance of PEG-based conjugates after intra-articular injection into the rat knee. [electronic resource]
Producer: 20200810Description: 270-281 p. digitalISSN:- 1878-7568
- Animals
- Biocompatible Materials -- chemistry
- Bosentan -- chemistry
- Drug Carriers -- chemistry
- Drug Liberation
- Endothelin-1 -- administration & dosage
- Fluorescent Dyes -- chemistry
- Injections, Intra-Articular
- Kinetics
- Knee Joint -- drug effects
- Lymphatic Vessels -- drug effects
- Male
- Optical Imaging
- Osteoarthritis -- drug therapy
- Peptides, Cyclic -- chemistry
- Polyethylene Glycols -- chemistry
- Rats
- Rats, Sprague-Dawley
- Synovial Fluid -- drug effects
- Tissue Distribution
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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