Activated MEK cooperates with Ink4a/Arf loss or Akt activation to induce gliomas in vivo. [electronic resource]
Producer: 20110519Description: 1341-50 p. digitalISSN:- 1476-5594
- Animals
- Apoptosis -- drug effects
- Benzamides -- pharmacology
- Brain Neoplasms -- genetics
- Cyclin-Dependent Kinase Inhibitor p16 -- genetics
- Diphenylamine -- analogs & derivatives
- Extracellular Signal-Regulated MAP Kinases -- genetics
- Genes, ras
- Glioma -- genetics
- Humans
- Imidazoles -- pharmacology
- MAP Kinase Signaling System
- Mice
- Mice, Transgenic
- Mitogen-Activated Protein Kinase Kinases -- antagonists & inhibitors
- Mitogen-Activated Protein Kinases -- genetics
- Neoplasms -- genetics
- Phosphoinositide-3 Kinase Inhibitors
- Proto-Oncogene Proteins c-akt -- genetics
- Quinolines -- pharmacology
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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