The Aurora A and B kinases are up-regulated in bone marrow-derived chronic lymphocytic leukemia cells and represent potential therapeutic targets. [electronic resource]
Producer: 20121212Description: 1246-54 p. digitalISSN:- 1592-8721
- Animals
- Antineoplastic Agents -- administration & dosage
- Apoptosis -- genetics
- Aurora Kinase A
- Aurora Kinases
- Bone Marrow Cells -- metabolism
- Cell Cycle -- genetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cluster Analysis
- Female
- Gene Expression Profiling
- Gene Expression Regulation, Leukemic
- Humans
- Leukemia, Lymphocytic, Chronic, B-Cell -- drug therapy
- Mice
- Mitosis -- genetics
- Piperazines -- administration & dosage
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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