Neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA receptor antagonist, in a range of animal models. [electronic resource]
Producer: 20071018Description: 151-60 p. digitalISSN:- 0007-1188
- Animals
- Anticonvulsants -- adverse effects
- Benzodiazepines -- metabolism
- Brain -- drug effects
- Brain Ischemia -- metabolism
- Cells, Cultured
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Excitatory Amino Acid Agonists -- toxicity
- Gerbillinae
- Male
- Membrane Potentials -- drug effects
- Mice
- Mice, Inbred DBA
- Neurons -- drug effects
- Neuroprotective Agents -- adverse effects
- Patch-Clamp Techniques
- Purkinje Cells -- drug effects
- Quisqualic Acid -- toxicity
- Rats
- Rats, Sprague-Dawley
- Rats, Wistar
- Receptors, AMPA -- antagonists & inhibitors
- Seizures -- etiology
- Telencephalon -- drug effects
- Time Factors
- alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid -- metabolism
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Publication Type: Comparative Study; Journal Article
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