Results
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The oxidative mechanism of action of ortho-quinone inhibitors of protein-tyrosine phosphatase alpha is mediated by hydrogen peroxide. [electronic resource] by
- Bova, Michael P
- Mattson, Matthew N
- Vasile, Stefan
- Tam, Danny
- Holsinger, Leslie
- Bremer, Meire
- Hui, Terence
- McMahon, Gerald
- Rice, Audie
- Fukuto, Jon M
Producer: 20040907
In:
Archives of biochemistry and biophysics vol. 429
Availability: No items available.
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4.
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Discovery of sulfonamide-pyrazole gamma-secretase inhibitors. [electronic resource] by
- Mattson, Matthew N
- Neitzel, Martin L
- Quincy, David A
- Semko, Christopher M
- Garofalo, Albert W
- Keim, Pamela S
- Konradi, Andrei W
- Pleiss, Michael A
- Sham, Hing L
- Brigham, Elizabeth F
- Goldbach, Erich G
- Zhang, Hongbin
- Sauer, John-Michael
- Basi, Guriqbal S
Producer: 20100705
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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5.
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Design, synthesis and structure-activity relationship of novel [3.3.1] bicyclic sulfonamide-pyrazoles as potent γ-secretase inhibitors. [electronic resource] by
- Aubele, Danielle L
- Truong, Anh P
- Dressen, Darren B
- Probst, Gary D
- Bowers, Simeon
- Mattson, Matthew N
- Semko, Chris M
- Sun, Minghua
- Garofalo, Albert W
- Konradi, Andrei W
- Sham, Hing L
- Zmolek, Wes
- Wong, Karina
- Goldbach, Erich
- Quinn, Kevin P
- Sauer, John-Michael
- Brigham, Elizabeth F
- Wallace, William
- Nguyen, Lan
- Bova, Michael P
- Hemphill, Susanna S
- Basi, Guriqbal
Producer: 20120416
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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6.
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Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease. [electronic resource] by
- Basi, Guriqbal S
- Hemphill, Susanna
- Brigham, Elizabeth F
- Liao, Anna
- Aubele, Danielle L
- Baker, Jeanne
- Barbour, Robin
- Bova, Michael
- Chen, Xiao-Hua
- Dappen, Michael S
- Eichenbaum, Tovah
- Goldbach, Erich
- Hawkinson, Jon
- Lawler-Herbold, Rose
- Hu, Kang
- Hui, Terence
- Jagodzinski, Jacek J
- Keim, Pamela S
- Kholodenko, Dora
- Latimer, Lee H
- Lee, Mike
- Marugg, Jennifer
- Mattson, Matthew N
- McCauley, Scott
- Miller, James L
- Motter, Ruth
- Mutter, Linda
- Neitzel, Martin L
- Ni, Huifang
- Nguyen, Lan
- Quinn, Kevin
- Ruslim, Lany
- Semko, Christopher M
- Shapiro, Paul
- Smith, Jenifer
- Soriano, Ferdie
- Szoke, Balazs
- Tanaka, Kevin
- Tang, Pearl
- Tucker, John A
- Ye, Xiacong Michael
- Yu, Mei
- Wu, Jing
- Xu, Ying-Zi
- Garofalo, Albert W
- Sauer, John Michael
- Konradi, Andrei W
- Ness, Daniel
- Shopp, George
- Pleiss, Michael A
- Freedman, Stephen B
- Schenk, Dale
Producer: 20110714
In:
Alzheimer's research & therapy vol. 2
Availability: No items available.
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7.
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Discovery of (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline (ELND007): metabolically stable γ-secretase Inhibitors that selectively inhibit the production of amyloid-β over Notch. [electronic resource] by
- Probst, Gary
- Aubele, Danielle L
- Bowers, Simeon
- Dressen, Darren
- Garofalo, Albert W
- Hom, Roy K
- Konradi, Andrei W
- Marugg, Jennifer L
- Mattson, Matthew N
- Neitzel, Martin L
- Semko, Chris M
- Sham, Hing L
- Smith, Jenifer
- Sun, Minghua
- Truong, Anh P
- Ye, Xiaocong M
- Xu, Ying-Zi
- Dappen, Michael S
- Jagodzinski, Jacek J
- Keim, Pamela S
- Peterson, Brian
- Latimer, Lee H
- Quincy, David
- Wu, Jing
- Goldbach, Erich
- Ness, Daniel K
- Quinn, Kevin P
- Sauer, John-Michael
- Wong, Karina
- Zhang, Hongbin
- Zmolek, Wes
- Brigham, Elizabeth F
- Kholodenko, Dora
- Hu, Kang
- Kwong, Grace T
- Lee, Michael
- Liao, Anna
- Motter, Ruth N
- Sacayon, Patricia
- Santiago, Pamela
- Willits, Christopher
- Bard, Frédérique
- Bova, Michael P
- Hemphill, Susanna S
- Nguyen, Lam
- Ruslim, Lany
- Tanaka, Kevin
- Tanaka, Pearl
- Wallace, William
- Yednock, Ted A
- Basi, Guriqbal S
Producer: 20140310
In:
Journal of medicinal chemistry vol. 56
Availability: No items available.
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