Structural elucidation of Leuprolide and its analogues in solution: insight into their bioactive conformation. [electronic resource]
Producer: 20110222Description: 1147-60 p. digitalISSN:- 1438-2199
- Antineoplastic Agents, Hormonal -- chemical synthesis
- Cell Proliferation -- drug effects
- Dimethyl Sulfoxide -- chemistry
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Gonadotropin-Releasing Hormone -- agonists
- Humans
- Leuprolide -- analogs & derivatives
- Magnetic Resonance Spectroscopy
- Models, Molecular
- Molecular Conformation
- Molecular Dynamics Simulation
- Solutions
- Structure-Activity Relationship
- Tumor Cells, Cultured
- Water -- chemistry
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Publication Type: Journal Article
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