Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons. [electronic resource]
Producer: 20090929Description: 499-506 p. digitalISSN:- 1090-2430
- Animals
- Behavior, Animal -- drug effects
- Carrier Proteins -- therapeutic use
- Cytokines -- therapeutic use
- Disease Models, Animal
- Dopamine -- metabolism
- Dose-Response Relationship, Drug
- Glial Cell Line-Derived Neurotrophic Factor -- genetics
- Male
- Mitogen-Activated Protein Kinase Kinases -- metabolism
- Motor Activity -- drug effects
- Neurons -- drug effects
- Oxidopamine
- Parkinson Disease, Secondary -- chemically induced
- Rats
- Rats, Wistar
- Sequence Deletion -- genetics
- Stereotyped Behavior -- drug effects
- Substantia Nigra -- pathology
- Tissue Distribution -- drug effects
- Tyrosine 3-Monooxygenase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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