Antagonism of the prostaglandin E2 EP1 receptor in MDCK cells increases growth through activation of Akt and the epidermal growth factor receptor. [electronic resource]
Producer: 20150326Description: F539-50 p. digitalISSN:- 1522-1466
- Animals
- Bridged Bicyclo Compounds -- pharmacology
- Caproates -- pharmacology
- Cell Proliferation -- drug effects
- Dogs
- ErbB Receptors -- antagonists & inhibitors
- Heterocyclic Compounds, 3-Ring -- pharmacology
- Hydrazines -- pharmacology
- Ibuprofen -- pharmacology
- Kidney -- drug effects
- Madin Darby Canine Kidney Cells
- Oxazepines -- pharmacology
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Quinazolines -- pharmacology
- Receptors, Prostaglandin E, EP1 Subtype -- antagonists & inhibitors
- Receptors, Prostaglandin E, EP2 Subtype -- physiology
- Receptors, Prostaglandin E, EP4 Subtype -- physiology
- Signal Transduction -- physiology
- Tyrphostins -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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