OTX008, a selective small-molecule inhibitor of galectin-1, downregulates cancer cell proliferation, invasion and tumour angiogenesis. [electronic resource]
Producer: 20150102Description: 2463-77 p. digitalISSN:- 1879-0852
- Animals
- Apoptosis -- drug effects
- Calixarenes -- pharmacology
- Cell Growth Processes -- drug effects
- Cell Line, Tumor
- Down-Regulation -- drug effects
- Drug Screening Assays, Antitumor
- Female
- Galectin 1 -- antagonists & inhibitors
- HT29 Cells
- Humans
- MCF-7 Cells
- Mice
- Mice, Nude
- Neoplasms -- blood supply
- Neovascularization, Pathologic -- drug therapy
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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