Mortality in adult intensive care patients with severe systemic inflammatory response syndromes is strongly associated with the hypo-immune TNF -238A polymorphism. [electronic resource]
Producer: 20100212Description: 657-62 p. digitalISSN:- 1432-1211
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Alleles
- England -- epidemiology
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Haplotypes
- Hospital Mortality
- Humans
- Immunity, Innate -- genetics
- Inflammation -- genetics
- Intensive Care Units -- statistics & numerical data
- Intramolecular Oxidoreductases -- genetics
- Lymphotoxin-alpha -- genetics
- Macrophage Migration-Inhibitory Factors -- genetics
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Systemic Inflammatory Response Syndrome -- genetics
- Toll-Like Receptor 4 -- genetics
- Tumor Necrosis Factor-alpha -- genetics
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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