Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways. [electronic resource]
Producer: 20051110Description: 1329-43 p. digitalISSN:- 1350-9047
- Animals
- Apoptosis -- drug effects
- Brain-Derived Neurotrophic Factor -- pharmacology
- Caspase 3
- Caspases -- biosynthesis
- Cell Survival
- Down-Regulation -- drug effects
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Glutamic Acid -- toxicity
- Hippocampus -- cytology
- MAP Kinase Signaling System -- drug effects
- Neurons -- cytology
- Neuroprotective Agents -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Rats
- Rats, Wistar
- Transfection
- ras Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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