A tyrosine kinase inhibitor, beta-hydroxyisovalerylshikonin, induced apoptosis in human lung cancer DMS114 cells through reduction of dUTP nucleotidohydrolase activity. [electronic resource]
Producer: 20080404Description: 41-50 p. digitalISSN:- 0006-3002
- Amino Acid Sequence
- Antineoplastic Agents -- pharmacology
- Antioxidants -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Deoxyuracil Nucleotides -- genetics
- Enzyme Activation -- drug effects
- Fluorouracil -- pharmacology
- Humans
- Lung Neoplasms -- enzymology
- Molecular Sequence Data
- Naphthoquinones -- pharmacology
- Phosphoproteins -- metabolism
- Protein Kinase Inhibitors -- pharmacology
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Pyrophosphatases -- chemistry
- RNA, Small Interfering -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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