c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer. [electronic resource]
Producer: 20120504Description: 869-83 p. digitalISSN:- 1476-5594
- Animals
- Apoptosis -- genetics
- BRCA1 Protein -- genetics
- Breast Neoplasms -- genetics
- Cell Differentiation -- genetics
- Cell Proliferation
- Cell Survival -- genetics
- Cells, Cultured
- Epithelial Cells -- metabolism
- Estrogen Receptor alpha -- genetics
- Female
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- Humans
- Mammary Glands, Animal -- cytology
- Mammary Neoplasms, Experimental -- genetics
- Mice
- Mutation
- NIH 3T3 Cells
- Proto-Oncogene Proteins c-kit -- genetics
- RNA Interference
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- genetics
- Stem Cells -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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