Parallel microarray profiling identifies ErbB4 as a determinant of cyst growth in ADPKD and a prognostic biomarker for disease progression. [electronic resource]
Producer: 20170712Description: F577-F588 p. digitalISSN:- 1522-1466
- Animals
- Case-Control Studies
- Cell Proliferation -- drug effects
- Disease Models, Animal
- Disease Progression
- Gene Expression Profiling -- methods
- Genetic Association Studies
- Genetic Markers
- Genetic Predisposition to Disease
- HEK293 Cells
- Humans
- Kidney -- drug effects
- Mice, Knockout
- MicroRNAs -- genetics
- Mutation
- Neuregulin-1 -- pharmacology
- Oligonucleotide Array Sequence Analysis
- Phenotype
- Polycystic Kidney, Autosomal Dominant -- genetics
- RNA Interference
- Receptor, ErbB-4 -- agonists
- Signal Transduction
- TRPP Cation Channels -- deficiency
- Transcriptional Activation
- Transfection
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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