Results
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2.
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N-aryl-benzimidazolones as novel small molecule HSP90 inhibitors. [electronic resource] by
- Bruncko, Milan
- Tahir, Stephen K
- Song, Xiaohong
- Chen, Jun
- Ding, Hong
- Huth, Jeffrey R
- Jin, Sha
- Judge, Russell A
- Madar, David J
- Park, Chang H
- Park, Cheol-Min
- Petros, Andrew M
- Tse, Christin
- Rosenberg, Saul H
- Elmore, Steven W
Producer: 20110314
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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3.
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Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors. [electronic resource] by
- Longenecker, Kenton L
- Stewart, Kent D
- Madar, David J
- Jakob, Clarissa G
- Fry, Elizabeth H
- Wilk, Sherwin
- Lin, Chun W
- Ballaron, Stephen J
- Stashko, Michael A
- Lubben, Thomas H
- Yong, Hong
- Pireh, Daisy
- Pei, Zhonghua
- Basha, Fatima
- Wiedeman, Paul E
- von Geldern, Thomas W
- Trevillyan, James M
- Stoll, Vincent S
Producer: 20060728
In:
Biochemistry vol. 45
Availability: No items available.
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4.
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Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit. [electronic resource] by
- Backes, Bradley J
- Longenecker, Kenton
- Hamilton, Gregory L
- Stewart, Kent
- Lai, Chunqiu
- Kopecka, Hana
- von Geldern, Thomas W
- Madar, David J
- Pei, Zhonghua
- Lubben, Thomas H
- Zinker, Bradley A
- Tian, Zhenping
- Ballaron, Stephen J
- Stashko, Michael A
- Mika, Amanda K
- Beno, David W A
- Kempf-Grote, Anita J
- Black-Schaefer, Candace
- Sham, Hing L
- Trevillyan, James M
Producer: 20070725
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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5.
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Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. [electronic resource] by
- Pei, Zhonghua
- Li, Xiaofeng
- von Geldern, Thomas W
- Madar, David J
- Longenecker, Kenton
- Yong, Hong
- Lubben, Thomas H
- Stewart, Kent D
- Zinker, Bradley A
- Backes, Bradley J
- Judd, Andrew S
- Mulhern, Mathew
- Ballaron, Stephen J
- Stashko, Michael A
- Mika, Amanda K
- Beno, David W A
- Reinhart, Glenn A
- Fryer, Ryan M
- Preusser, Lee C
- Kempf-Grote, Anita J
- Sham, Hing L
- Trevillyan, James M
Producer: 20061205
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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6.
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Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors. [electronic resource] by
- Pei, Zhonghua
- Li, Xiaofeng
- Longenecker, Kenton
- von Geldern, Thomas W
- Wiedeman, Paul E
- Lubben, Thomas H
- Zinker, Bradley A
- Stewart, Kent
- Ballaron, Stephen J
- Stashko, Michael A
- Mika, Amanda K
- Beno, David W A
- Long, Michelle
- Wells, Heidi
- Kempf-Grote, Anita J
- Madar, David J
- McDermott, Todd S
- Bhagavatula, Lakshmi
- Fickes, Michael G
- Pireh, Daisy
- Solomon, Larry R
- Lake, Marc R
- Edalji, Rohinton
- Fry, Elizabeth H
- Sham, Hing L
- Trevillyan, James M
Producer: 20060731
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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7.
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Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]- 4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279): a very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetes. [electronic resource] by
- Madar, David J
- Kopecka, Hana
- Pireh, Daisy
- Yong, Hong
- Pei, Zhonghua
- Li, Xiaofeng
- Wiedeman, Paul E
- Djuric, Stevan W
- Von Geldern, Thomas W
- Fickes, Michael G
- Bhagavatula, Lakshmi
- McDermott, Todd
- Wittenberger, Steven
- Richards, Steven J
- Longenecker, Kenton L
- Stewart, Kent D
- Lubben, Thomas H
- Ballaron, Stephen J
- Stashko, Michael A
- Long, Michelle A
- Wells, Heidi
- Zinker, Bradley A
- Mika, Amanda K
- Beno, David W A
- Kempf-Grote, Anita J
- Polakowski, James
- Segreti, Jason
- Reinhart, Glenn A
- Fryer, Ryan M
- Sham, Hing L
- Trevillyan, James M
Producer: 20061204
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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