Redesign of the PAK1 autoinhibitory domain for enhanced stability and affinity in biosensor applications. [electronic resource]
Producer: 20111207Description: 513-22 p. digitalISSN:- 1089-8638
- Amino Acid Sequence
- Binding Sites
- Biosensing Techniques
- Circular Dichroism
- Computer-Aided Design
- Enzyme Activation
- Fluorescence Polarization
- Green Fluorescent Proteins -- chemistry
- Humans
- Models, Molecular
- Molecular Dynamics Simulation
- Molecular Sequence Data
- Protein Binding
- Protein Conformation
- Sequence Homology, Amino Acid
- Software
- p21-Activated Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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