Montelukast reduces eosinophilic inflammation by inhibiting both epithelial cell cytokine secretion (GM-CSF, IL-6, IL-8) and eosinophil survival. [electronic resource]
Producer: 20110302Description: 403-11 p. digitalISSN:- 0393-974X
- Acetates -- pharmacology
- Adult
- Animals
- Cattle
- Cell Survival -- drug effects
- Cyclopropanes
- Cytokines -- biosynthesis
- Eosinophilia -- drug therapy
- Eosinophils -- drug effects
- Epithelial Cells -- drug effects
- Female
- Granulocyte-Macrophage Colony-Stimulating Factor -- biosynthesis
- Humans
- In Vitro Techniques
- Inflammation -- drug therapy
- Interleukin-6 -- biosynthesis
- Interleukin-8 -- biosynthesis
- Leukotriene Antagonists -- pharmacology
- Male
- Middle Aged
- Nasal Mucosa -- drug effects
- Nasal Polyps -- drug therapy
- Quinolines -- pharmacology
- Rhinitis -- drug therapy
- Sulfides
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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