The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity. [electronic resource]
Producer: 20150805Description: e1001895 p. digitalISSN:- 1545-7885
- Aged
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins -- genetics
- Cell Line
- Female
- Forkhead Transcription Factors -- metabolism
- Humans
- Huntington Disease -- etiology
- Male
- Mice
- Mice, Transgenic
- Middle Aged
- Neurons -- metabolism
- Oligonucleotide Array Sequence Analysis
- Presenilin-1 -- metabolism
- Receptor Protein-Tyrosine Kinases -- genetics
- Receptors, Wnt -- metabolism
- Serotonin Plasma Membrane Transport Proteins -- genetics
- Wnt Signaling Pathway
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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