Inactivation of Adenomatous Polyposis Coli Reduces Bile Acid/Farnesoid X Receptor Expression through Fxr gene CpG Methylation in Mouse Colon Tumors and Human Colon Cancer Cells. [electronic resource]
Producer: 20160609Description: 236-42 p. digitalISSN:- 1541-6100
- Adenocarcinoma -- genetics
- Adenomatous Polyposis Coli -- genetics
- Animals
- Bile Acids and Salts -- metabolism
- Colon -- metabolism
- Colonic Neoplasms -- genetics
- Cyclooxygenase 2 -- metabolism
- DNA Methylation
- Gene Expression
- Gene Silencing
- Genes, APC
- HCT116 Cells
- HT29 Cells
- Humans
- Mice, Inbred C57BL
- Promoter Regions, Genetic
- Proto-Oncogene Proteins c-myc -- metabolism
- Receptors, Cytoplasmic and Nuclear -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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