Identification of New Shikonin Derivatives as Antitumor Agents Targeting STAT3 SH2 Domain. [electronic resource]
Producer: 20181218Description: 2863 p. digitalISSN:- 2045-2322
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Humans
- Magnetic Resonance Spectroscopy
- Membrane Potential, Mitochondrial -- drug effects
- Molecular Docking Simulation
- Molecular Dynamics Simulation
- Molecular Structure
- Naphthoquinones -- chemical synthesis
- Protein Transport
- STAT3 Transcription Factor -- antagonists & inhibitors
- Structure-Activity Relationship
- src Homology Domains -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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