Estrogen receptor α promotes Cav1.2 ubiquitination and degradation in neuronal cells and in APP/PS1 mice. [electronic resource]
Producer: 20200707Description: e12961 p. digitalISSN:- 1474-9726
- Alzheimer Disease -- drug therapy
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Calcium Channels, L-Type -- metabolism
- Cell Line, Tumor
- Cognitive Dysfunction -- drug therapy
- Disease Models, Animal
- Estradiol -- pharmacology
- Estrogen Receptor alpha -- agonists
- Female
- Gene Knockdown Techniques
- Humans
- Leupeptins -- pharmacology
- Mice -- embryology
- Mice, Inbred C57BL
- Mice, Transgenic
- Neurons -- metabolism
- Oligopeptides -- genetics
- Phenols -- pharmacology
- Proteasome Inhibitors -- pharmacology
- Proteolysis -- drug effects
- Proto-Oncogene Proteins c-mdm2 -- genetics
- Pyrazoles -- pharmacology
- Transfection
- Ubiquitin -- metabolism
- Ubiquitination -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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