The iron chelator Deferasirox causes severe mitochondrial swelling without depolarization due to a specific effect on inner membrane permeability. [electronic resource]
Producer: 20201117Description: 1577 p. digitalISSN:- 2045-2322
- Animals
- Cell Line
- Deferasirox -- pharmacology
- Humans
- Iron Chelating Agents -- pharmacology
- Kidney -- drug effects
- Male
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Mice, Inbred C57BL
- Microscopy, Electron
- Mitochondria -- drug effects
- Mitochondrial Membranes -- drug effects
- Permeability -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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