Gabapentin-lactam, but not gabapentin, reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington's disease. [electronic resource]
Producer: 20050414Description: 131-9 p. digitalISSN:- 0028-1298
- Amines -- therapeutic use
- Animals
- Anticonvulsants -- therapeutic use
- Aza Compounds -- blood
- Corpus Striatum -- metabolism
- Cyclohexanecarboxylic Acids -- therapeutic use
- Disease Models, Animal
- Female
- Gabapentin
- Hippocampus -- metabolism
- Huntington Disease -- drug therapy
- Injections, Subcutaneous
- Male
- Mice
- Mice, Transgenic
- Motor Activity -- drug effects
- Neuroprotective Agents -- therapeutic use
- Spiro Compounds -- blood
- Survival Rate
- gamma-Aminobutyric Acid -- therapeutic use
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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