Discovery and optimization of substituted 1-(1-phenyl-1H-pyrazol-3-yl)methanamines as potent and efficacious type II calcimimetics. [electronic resource]
Producer: 20091215Description: 6535-8 p. digitalISSN:- 1520-4804
- Administration, Oral
- Aniline Compounds -- chemical synthesis
- Animals
- Biological Availability
- Cell Line
- Crystallography, X-Ray
- Humans
- Hyperparathyroidism, Secondary -- drug therapy
- Male
- Methylamines -- chemical synthesis
- Molecular Structure
- Parathyroid Hormone -- blood
- Phenethylamines
- Propylamines
- Pyrazoles -- chemical synthesis
- Rats
- Rats, Sprague-Dawley
- Receptors, Calcium-Sensing -- agonists
- Stereoisomerism
- Structure-Activity Relationship
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Publication Type: Journal Article
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