Results
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Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways. [electronic resource] by
- Rothenberg, S Michael
- Concannon, Kyle
- Cullen, Sarah
- Boulay, Gaylor
- Turke, Alexa B
- Faber, Anthony C
- Lockerman, Elizabeth L
- Rivera, Miguel N
- Engelman, Jeffrey A
- Maheswaran, Shyamala
- Haber, Daniel A
Producer: 20151214
In:
eLife vol. 4
Availability: No items available.
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5.
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Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib. [electronic resource] by
- Katayama, Ryohei
- Friboulet, Luc
- Koike, Sumie
- Lockerman, Elizabeth L
- Khan, Tahsin M
- Gainor, Justin F
- Iafrate, A John
- Takeuchi, Kengo
- Taiji, Makoto
- Okuno, Yasushi
- Fujita, Naoya
- Engelman, Jeffrey A
- Shaw, Alice T
Producer: 20150709
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 20
Availability: No items available.
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6.
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CDK 4/6 inhibitors sensitize PIK3CA mutant breast cancer to PI3K inhibitors. [electronic resource] by
- Vora, Sadhna R
- Juric, Dejan
- Kim, Nayoon
- Mino-Kenudson, Mari
- Huynh, Tiffany
- Costa, Carlotta
- Lockerman, Elizabeth L
- Pollack, Sarah F
- Liu, Manway
- Li, Xiaoyan
- Lehar, Joseph
- Wiesmann, Marion
- Wartmann, Markus
- Chen, Yan
- Cao, Z Alexander
- Pinzon-Ortiz, Maria
- Kim, Sunkyu
- Schlegel, Robert
- Huang, Alan
- Engelman, Jeffrey A
Producer: 20140912
In:
Cancer cell vol. 26
Availability: No items available.
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7.
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The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer. [electronic resource] by
- Friboulet, Luc
- Li, Nanxin
- Katayama, Ryohei
- Lee, Christian C
- Gainor, Justin F
- Crystal, Adam S
- Michellys, Pierre-Yves
- Awad, Mark M
- Yanagitani, Noriko
- Kim, Sungjoon
- Pferdekamper, AnneMarie C
- Li, Jie
- Kasibhatla, Shailaja
- Sun, Frank
- Sun, Xiuying
- Hua, Su
- McNamara, Peter
- Mahmood, Sidra
- Lockerman, Elizabeth L
- Fujita, Naoya
- Nishio, Makoto
- Harris, Jennifer L
- Shaw, Alice T
- Engelman, Jeffrey A
Producer: 20150112
In:
Cancer discovery vol. 4
Availability: No items available.
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8.
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Acquired resistance to crizotinib from a mutation in CD74-ROS1. [electronic resource] by
- Awad, Mark M
- Katayama, Ryohei
- McTigue, Michele
- Liu, Wei
- Deng, Ya-Li
- Brooun, Alexei
- Friboulet, Luc
- Huang, Donghui
- Falk, Matthew D
- Timofeevski, Sergei
- Wilner, Keith D
- Lockerman, Elizabeth L
- Khan, Tahsin M
- Mahmood, Sidra
- Gainor, Justin F
- Digumarthy, Subba R
- Stone, James R
- Mino-Kenudson, Mari
- Christensen, James G
- Iafrate, A John
- Engelman, Jeffrey A
- Shaw, Alice T
Producer: 20130628
In:
The New England journal of medicine vol. 368
Availability: No items available.
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9.
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Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor. [electronic resource] by
- Piotrowska, Zofia
- Niederst, Matthew J
- Karlovich, Chris A
- Wakelee, Heather A
- Neal, Joel W
- Mino-Kenudson, Mari
- Fulton, Linnea
- Hata, Aaron N
- Lockerman, Elizabeth L
- Kalsy, Anuj
- Digumarthy, Subba
- Muzikansky, Alona
- Raponi, Mitch
- Garcia, Angel R
- Mulvey, Hillary E
- Parks, Melissa K
- DiCecca, Richard H
- Dias-Santagata, Dora
- Iafrate, A John
- Shaw, Alice T
- Allen, Andrew R
- Engelman, Jeffrey A
- Sequist, Lecia V
Producer: 20160421
In:
Cancer discovery vol. 5
Availability: No items available.
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10.
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EGF816 Exerts Anticancer Effects in Non-Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor. [electronic resource] by
- Jia, Yong
- Juarez, Jose
- Li, Jie
- Manuia, Mari
- Niederst, Matthew J
- Tompkins, Celin
- Timple, Noelito
- Vaillancourt, Mei-Ting
- Pferdekamper, AnneMarie Culazzo
- Lockerman, Elizabeth L
- Li, Chun
- Anderson, Jennifer
- Costa, Carlotta
- Liao, Debbie
- Murphy, Eric
- DiDonato, Michael
- Bursulaya, Badry
- Lelais, Gerald
- Barretina, Jordi
- McNeill, Matthew
- Epple, Robert
- Marsilje, Thomas H
- Pathan, Nuzhat
- Engelman, Jeffrey A
- Michellys, Pierre-Yves
- McNamara, Peter
- Harris, Jennifer
- Bender, Steven
- Kasibhatla, Shailaja
Producer: 20160725
In:
Cancer research vol. 76
Availability: No items available.
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11.
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Patient-derived models of acquired resistance can identify effective drug combinations for cancer. [electronic resource] by
- Crystal, Adam S
- Shaw, Alice T
- Sequist, Lecia V
- Friboulet, Luc
- Niederst, Matthew J
- Lockerman, Elizabeth L
- Frias, Rosa L
- Gainor, Justin F
- Amzallag, Arnaud
- Greninger, Patricia
- Lee, Dana
- Kalsy, Anuj
- Gomez-Caraballo, Maria
- Elamine, Leila
- Howe, Emily
- Hur, Wooyoung
- Lifshits, Eugene
- Robinson, Hayley E
- Katayama, Ryohei
- Faber, Anthony C
- Awad, Mark M
- Ramaswamy, Sridhar
- Mino-Kenudson, Mari
- Iafrate, A John
- Benes, Cyril H
- Engelman, Jeffrey A
Producer: 20150115
In:
Science (New York, N.Y.) vol. 346
Availability: No items available.
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12.
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Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations. [electronic resource] by
- Ahronian, Leanne G
- Sennott, Erin M
- Van Allen, Eliezer M
- Wagle, Nikhil
- Kwak, Eunice L
- Faris, Jason E
- Godfrey, Jason T
- Nishimura, Koki
- Lynch, Kerry D
- Mermel, Craig H
- Lockerman, Elizabeth L
- Kalsy, Anuj
- Gurski, Joseph M
- Bahl, Samira
- Anderka, Kristin
- Green, Lisa M
- Lennon, Niall J
- Huynh, Tiffany G
- Mino-Kenudson, Mari
- Getz, Gad
- Dias-Santagata, Dora
- Iafrate, A John
- Engelman, Jeffrey A
- Garraway, Levi A
- Corcoran, Ryan B
Producer: 20160112
In:
Cancer discovery vol. 5
Availability: No items available.
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13.
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RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer. [electronic resource] by
- Niederst, Matthew J
- Sequist, Lecia V
- Poirier, John T
- Mermel, Craig H
- Lockerman, Elizabeth L
- Garcia, Angel R
- Katayama, Ryohei
- Costa, Carlotta
- Ross, Kenneth N
- Moran, Teresa
- Howe, Emily
- Fulton, Linnea E
- Mulvey, Hillary E
- Bernardo, Lindsay A
- Mohamoud, Farhiya
- Miyoshi, Norikatsu
- VanderLaan, Paul A
- Costa, Daniel B
- Jänne, Pasi A
- Borger, Darrell R
- Ramaswamy, Sridhar
- Shioda, Toshi
- Iafrate, Anthony J
- Getz, Gad
- Rudin, Charles M
- Mino-Kenudson, Mari
- Engelman, Jeffrey A
Producer: 20160209
In:
Nature communications vol. 6
Availability: No items available.
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14.
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Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer. [electronic resource] by
- Gainor, Justin F
- Dardaei, Leila
- Yoda, Satoshi
- Friboulet, Luc
- Leshchiner, Ignaty
- Katayama, Ryohei
- Dagogo-Jack, Ibiayi
- Gadgeel, Shirish
- Schultz, Katherine
- Singh, Manrose
- Chin, Emily
- Parks, Melissa
- Lee, Dana
- DiCecca, Richard H
- Lockerman, Elizabeth
- Huynh, Tiffany
- Logan, Jennifer
- Ritterhouse, Lauren L
- Le, Long P
- Muniappan, Ashok
- Digumarthy, Subba
- Channick, Colleen
- Keyes, Colleen
- Getz, Gad
- Dias-Santagata, Dora
- Heist, Rebecca S
- Lennerz, Jochen
- Sequist, Lecia V
- Benes, Cyril H
- Iafrate, A John
- Mino-Kenudson, Mari
- Engelman, Jeffrey A
- Shaw, Alice T
Producer: 20171027
In:
Cancer discovery vol. 6
Availability: No items available.
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15.
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Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition. [electronic resource] by
- Hata, Aaron N
- Niederst, Matthew J
- Archibald, Hannah L
- Gomez-Caraballo, Maria
- Siddiqui, Faria M
- Mulvey, Hillary E
- Maruvka, Yosef E
- Ji, Fei
- Bhang, Hyo-eun C
- Krishnamurthy Radhakrishna, Viveksagar
- Siravegna, Giulia
- Hu, Haichuan
- Raoof, Sana
- Lockerman, Elizabeth
- Kalsy, Anuj
- Lee, Dana
- Keating, Celina L
- Ruddy, David A
- Damon, Leah J
- Crystal, Adam S
- Costa, Carlotta
- Piotrowska, Zofia
- Bardelli, Alberto
- Iafrate, Anthony J
- Sadreyev, Ruslan I
- Stegmeier, Frank
- Getz, Gad
- Sequist, Lecia V
- Faber, Anthony C
- Engelman, Jeffrey A
Producer: 20160719
In:
Nature medicine vol. 22
Availability: No items available.
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16.
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Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM. [electronic resource] by
- Song, Kyung-A
- Niederst, Matthew J
- Lochmann, Timothy L
- Hata, Aaron N
- Kitai, Hidenori
- Ham, Jungoh
- Floros, Konstantinos V
- Hicks, Mark A
- Hu, Haichuan
- Mulvey, Hillary E
- Drier, Yotam
- Heisey, Daniel A R
- Hughes, Mark T
- Patel, Neha U
- Lockerman, Elizabeth L
- Garcia, Angel
- Gillepsie, Shawn
- Archibald, Hannah L
- Gomez-Caraballo, Maria
- Nulton, Tara J
- Windle, Brad E
- Piotrowska, Zofia
- Sahingur, Sinem E
- Taylor, Shirley M
- Dozmorov, Mikhail
- Sequist, Lecia V
- Bernstein, Bradley
- Ebi, Hiromichi
- Engelman, Jeffrey A
- Faber, Anthony C
Producer: 20190613
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 24
Availability: No items available.
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