Alkyladenine DNA glycosylase deficiency uncouples alkylation-induced strand break generation from PARP-1 activation and glycolysis inhibition. [electronic resource]
Producer: 20201118Description: 2209 p. digitalISSN:- 2045-2322
- Acrylamides -- pharmacology
- Alkylation
- Animals
- Cells, Cultured
- Cytokines -- antagonists & inhibitors
- DNA Breaks -- drug effects
- DNA Glycosylases -- deficiency
- DNA Repair
- Fibroblasts
- Glycolysis -- drug effects
- Methyl Methanesulfonate -- pharmacology
- Mice
- Mice, Knockout
- NAD -- metabolism
- Nicotinamide Phosphoribosyltransferase -- antagonists & inhibitors
- Piperidines -- pharmacology
- Poly (ADP-Ribose) Polymerase-1 -- metabolism
- Primary Cell Culture
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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