Inhibition of immune checkpoints PD-1, CTLA-4, and IDO1 coordinately induces immune-mediated liver injury in mice. [electronic resource]
Producer: 20200203Description: e0217276 p. digitalISSN:- 1932-6203
- Animals
- CD8-Positive T-Lymphocytes -- immunology
- CTLA-4 Antigen -- antagonists & inhibitors
- Disease Models, Animal
- Female
- Hepatocytes -- pathology
- Humans
- Indoleamine-Pyrrole 2,3,-Dioxygenase -- antagonists & inhibitors
- Ipilimumab -- administration & dosage
- Liver -- immunology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Nivolumab -- administration & dosage
- Oximes -- administration & dosage
- Programmed Cell Death 1 Receptor -- antagonists & inhibitors
- Sulfonamides -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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