Results
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1.
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Ability of Bruton's Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling. [electronic resource] by
- Bender, Andrew T
- Gardberg, Anna
- Pereira, Albertina
- Johnson, Theresa
- Wu, Yin
- Grenningloh, Roland
- Head, Jared
- Morandi, Federica
- Haselmayer, Philipp
- Liu-Bujalski, Lesley
Producer: 20170501
In:
Molecular pharmacology vol. 91
Availability: No items available.
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2.
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Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models. [electronic resource] by
- Haselmayer, Philipp
- Camps, Montserrat
- Liu-Bujalski, Lesley
- Nguyen, Ngan
- Morandi, Federica
- Head, Jared
- O'Mahony, Alison
- Zimmerli, Simone C
- Bruns, Lisa
- Bender, Andrew T
- Schroeder, Patricia
- Grenningloh, Roland
Producer: 20191230
In:
Journal of immunology (Baltimore, Md. : 1950) vol. 202
Availability: No items available.
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3.
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Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk. [electronic resource] by
- Caldwell, Richard
- Liu-Bujalski, Lesley
- Qiu, Hui
- Mochalkin, Igor
- Jones, Reinaldo
- Neagu, Constantin
- Goutopoulos, Andreas
- Grenningloh, Roland
- Johnson, Theresa
- Sherer, Brian
- Gardberg, Anna
- Follis, Ariele Viacava
- Morandi, Federica
- Head, Jared
Producer: 20190514
In:
Bioorganic & medicinal chemistry letters vol. 28
Availability: No items available.
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4.
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Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hit. [electronic resource] by
- Qiu, Hui
- Liu-Bujalski, Lesley
- Caldwell, Richard D
- Follis, Ariele Viacava
- Gardberg, Anna
- Goutopoulos, Andreas
- Grenningloh, Roland
- Head, Jared
- Johnson, Theresa
- Jones, Reinaldo
- Mochalkin, Igor
- Morandi, Federica
- Neagu, Constantin
- Sherer, Brian
Producer: 20190311
In:
Bioorganic & medicinal chemistry letters vol. 28
Availability: No items available.
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5.
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Discovery of Affinity-Based Probes for Btk Occupancy Assays. [electronic resource] by
- Qiu, Hui
- Caldwell, Richard
- Liu-Bujalski, Lesley
- Goutopoulos, Andreas
- Jones, Reinaldo
- Potnick, Justin
- Sherer, Brian
- Bender, Andrew
- Grenningloh, Roland
- Xu, Daigen
- Gardberg, Anna
- Mochalkin, Igor
- Johnson, Theresa
- Viacava Follis, Ariele
- Head, Jared
- Morandi, Federica
Producer: 20191206
In:
ChemMedChem vol. 14
Availability: No items available.
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6.
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Btk inhibition treats TLR7/IFN driven murine lupus. [electronic resource] by
- Bender, Andrew T
- Pereira, Albertina
- Fu, Kai
- Samy, Eileen
- Wu, Yin
- Liu-Bujalski, Lesley
- Caldwell, Richard
- Chen, Yi-Ying
- Tian, Hui
- Morandi, Federica
- Head, Jared
- Koehler, Ursula
- Genest, Melinda
- Okitsu, Shinji L
- Xu, Daigen
- Grenningloh, Roland
Producer: 20160718
In:
Clinical immunology (Orlando, Fla.) vol. 164
Availability: No items available.
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7.
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Optimization of the efflux ratio and permeability of covalent irreversible BTK inhibitors. [electronic resource] by
- Qiu, Hui
- Liu-Bujalski, Lesley
- Caldwell, Richard D
- Viacava Follis, Ariele
- Gardberg, Anna
- Goutopoulos, Andreas
- Grenningloh, Roland
- Head, Jared
- Johnson, Theresa
- Jones, Christopher C V
- Jones, Reinaldo
- Mochalkin, Igor
- Morandi, Federica
- Neagu, Constantin
- Potnick, Justin
- Sherer, Brian
Producer: 20190603
In:
Bioorganic & medicinal chemistry letters vol. 28
Availability: No items available.
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8.
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SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors. [electronic resource] by
- Karra, Srinivasa
- Xiao, Yufang
- Chen, Xiaoling
- Liu-Bujalski, Lesley
- Huck, Bayard
- Sutton, Amanda
- Goutopoulos, Andreas
- Askew, Ben
- Josephson, Kristopher
- Jiang, Xuliang
- Shutes, Adam
- Shankar, Vikram
- Noonan, Tom
- Garcia-Berrios, Gaianne
- Dong, Rong
- Dhanabal, Mohanraj
- Tian, Hui
- Wang, Zhenxiong
- Clark, A
- Goodstal, Samantha
Producer: 20131126
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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9.
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Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases. [electronic resource] by
- Caldwell, Richard D
- Qiu, Hui
- Askew, Ben C
- Bender, Andrew T
- Brugger, Nadia
- Camps, Montserrat
- Dhanabal, Mohanraj
- Dutt, Vikram
- Eichhorn, Thomas
- Gardberg, Anna S
- Goutopoulos, Andreas
- Grenningloh, Roland
- Head, Jared
- Healey, Brian
- Hodous, Brian L
- Huck, Bayard R
- Johnson, Theresa L
- Jones, Christopher
- Jones, Reinaldo C
- Mochalkin, Igor
- Morandi, Federica
- Nguyen, Ngan
- Meyring, Michael
- Potnick, Justin R
- Santos, Dusica Cvetinovic
- Schmidt, Ralf
- Sherer, Brian
- Shutes, Adam
- Urbahns, Klaus
- Follis, Ariele Viacava
- Wegener, Ansgar A
- Zimmerli, Simone C
- Liu-Bujalski, Lesley
Producer: 20200629
In:
Journal of medicinal chemistry vol. 62
Availability: No items available.
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