Simulated Microgravity Disrupts Cytoskeleton Organization and Increases Apoptosis of Rat Neural Crest Stem Cells Via Upregulating CXCR4 Expression and RhoA-ROCK1-p38 MAPK-p53 Signaling. [electronic resource]
Producer: 20170911Description: 1172-93 p. digitalISSN:- 1557-8534
- Animals
- Apoptosis
- Biomarkers -- metabolism
- Caspase 3 -- metabolism
- Cell Adhesion
- Cell Membrane -- metabolism
- Cell Proliferation
- Cell Shape
- Cell Survival
- Cells, Cultured
- Cytoskeleton -- metabolism
- Female
- Neural Crest -- cytology
- Neural Stem Cells -- cytology
- Phosphorylation
- RNA, Messenger -- genetics
- RNA, Small Interfering -- metabolism
- Rats, Sprague-Dawley
- Receptors, CXCR4 -- genetics
- Signal Transduction
- Tumor Suppressor Protein p53 -- metabolism
- Up-Regulation
- Weightlessness Simulation
- p38 Mitogen-Activated Protein Kinases -- metabolism
- rho-Associated Kinases -- metabolism
- rhoA GTP-Binding Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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