A-432411, a novel indolinone compound that disrupts spindle pole formation and inhibits human cancer cell growth. [electronic resource]
Producer: 20051006Description: 562-8 p. digitalISSN:- 1535-7163
- Antineoplastic Agents -- chemistry
- Binding Sites
- Binding, Competitive
- Blotting, Western
- CDC2 Protein Kinase -- metabolism
- Cell Cycle
- Cell Death
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Separation
- Colchicine -- pharmacology
- Cyclin B -- chemistry
- Cyclin B1
- Dose-Response Relationship, Drug
- Endothelium, Vascular -- metabolism
- Flow Cytometry
- HeLa Cells
- Histones -- chemistry
- Humans
- Immunohistochemistry
- Indoles -- chemistry
- Microscopy, Fluorescence
- Microtubules -- chemistry
- Models, Chemical
- Neoplasm Proteins -- chemistry
- Pyrroles -- chemistry
- Securin
- Spindle Apparatus -- drug effects
- Time Factors
- Tubulin -- chemistry
- Tyrosine -- chemistry
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Publication Type: Journal Article
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