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Specific and dual antagonists of alpha(4)beta(1) and alpha(4)beta(7) integrins. [electronic resource] by
- Lin, Linus S
- Lanza, Thomas
- McCauley, Ermenegilda
- Van Riper, Gail
- Kidambi, Usha
- Cao, Jin
- Egger, Linda A
- Mumford, Richard A
- Schmidt, John A
- MacCoss, Malcolm
- Hagmann, William K
Producer: 20020322
In:
Bioorganic & medicinal chemistry letters vol. 12
Availability: No items available.
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7.
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Addressing the metabolic activation potential of new leads in drug discovery: a case study using ion trap mass spectrometry and tritium labeling techniques. [electronic resource] by
- Samuel, Koppara
- Yin, Wenji
- Stearns, Ralph A
- Tang, Yui S
- Chaudhary, Ashok G
- Jewell, James P
- Lanza, Thomas
- Lin, Linus S
- Hagmann, William K
- Evans, David C
- Kumar, Sanjeev
Producer: 20030409
In:
Journal of mass spectrometry : JMS vol. 38
Availability: No items available.
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8.
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Pyridinesulfonylureas and pyridinesulfonamides as selective bombesin receptor subtype-3 (BRS-3) agonists. [electronic resource] by
- Lo, Michael M-C
- Chobanian, Harry R
- Palyha, Oksana
- Kan, Yanqing
- Kelly, Theresa M
- Guan, Xiao-Ming
- Reitman, Marc L
- Dragovic, Jasminka
- Lyons, Kathryn A
- Nargund, Ravi P
- Lin, Linus S
Producer: 20110711
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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9.
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Conformational analysis and receptor docking of N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (taranabant, MK-0364), a novel, acyclic cannabinoid-1 receptor inverse agonist. [electronic resource] by
- Lin, Linus S
- Ha, Sookhee
- Ball, Richard G
- Tsou, Nancy N
- Castonguay, Laurie A
- Doss, George A
- Fong, Tung M
- Shen, Chun-Pyn
- Xiao, Jing Chen
- Goulet, Mark T
- Hagmann, William K
Producer: 20080613
In:
Journal of medicinal chemistry vol. 51
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10.
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Bioisosteric replacement of anilide with benzoxazole: potent and orally bioavailable antagonists of VLA-4. [electronic resource] by
- Lin, Linus S
- Lanza, Thomas J
- Castonguay, Laurie A
- Kamenecka, Theodore
- McCauley, Ermenegilda
- Van Riper, Gail
- Egger, Linda A
- Mumford, Richard A
- Tong, Xinchun
- MacCoss, Malcolm
- Schmidt, John A
- Hagmann, William K
Producer: 20041222
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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11.
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PET imaging studies in rhesus monkey with the cannabinoid-1 (CB1) receptor ligand [11C]CB-119. [electronic resource] by
- Hamill, Terence G
- Lin, Linus S
- Hagmann, William
- Liu, Ping
- Jewell, James
- Sanabria, Sandra
- Eng, WaiSi
- Ryan, Christine
- Fong, Tung M
- Connolly, Brett
- Vanko, Amy
- Hargreaves, Richard
- Goulet, Mark T
- Burns, H Donald
Producer: 20091022
In:
Molecular imaging and biology vol. 11
Availability: No items available.
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12.
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Discovery of XEN445: a potent and selective endothelial lipase inhibitor raises plasma HDL-cholesterol concentration in mice. [electronic resource] by
- Sun, Shaoyi
- Dean, Richard
- Jia, Qi
- Zenova, Alla
- Zhong, Jing
- Grayson, Celene
- Xie, Clark
- Lindgren, Andrea
- Samra, Pritpaul
- Sojo, Luis
- van Heek, Margaret
- Lin, Linus
- Percival, David
- Fu, Jian-Min
- Winther, Michael D
- Zhang, Zaihui
Producer: 20140922
In:
Bioorganic & medicinal chemistry vol. 21
Availability: No items available.
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13.
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Body temperature as a mouse pharmacodynamic response to bombesin receptor subtype-3 agonists and other potential obesity treatments. [electronic resource] by
- Metzger, Joseph M
- Gagen, Karen
- Raustad, Kate A
- Yang, Liming
- White, Amanda
- Wang, Sheng-Ping
- Craw, Stephanie
- Liu, Ping
- Lanza, Thomas
- Lin, Linus S
- Nargund, Ravi P
- Guan, Xiao-Ming
- Strack, Alison M
- Reitman, Marc L
Producer: 20101116
In:
American journal of physiology. Endocrinology and metabolism vol. 299
Availability: No items available.
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14.
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Synthesis and cannabinoid-1 receptor binding affinity of conformationally constrained analogs of taranabant. [electronic resource] by
- Kopka, Ihor E
- Lin, Linus S
- Jewell, James P
- Lanza, Thomas J
- Fong, Tung M
- Shen, Chun-Pyn
- Lao, Zhege J
- Ha, Sookhee
- Castonguay, Laurie G
- Van der Ploeg, Lex
- Goulet, Mark T
- Hagmann, William K
Producer: 20101110
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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15.
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Synthesis of 7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine and its analogs as bombesin receptor subtype-3 agonists. [electronic resource] by
- Guo, Cheng
- Guzzo, Peter R
- Hadden, Mark
- Sargent, Bruce J
- Yet, Larry
- Kan, Yanqing
- Palyha, Oksana
- Kelly, Theresa M
- Guan, Xiaoming
- Rosko, Kim
- Gagen, Karen
- Metzger, Joseph M
- Dragovic, Jasminka
- Lyons, Kathryn
- Lin, Linus S
- Nargund, Ravi P
Producer: 20100727
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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16.
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Synthesis and evaluation of N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists. [electronic resource] by
- Du, Wu
- Jewell, James P
- Lin, Linus S
- Colandrea, Vincent J
- Xiao, Jing C
- Lao, Julie
- Shen, Chun-Pyn
- Bateman, Thomas J
- Reddy, Vijay B G
- Ha, Sookhee N
- Shah, Shrenik K
- Fong, Tung M
- Hale, Jeffrey J
- Hagmann, William K
Producer: 20091124
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
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17.
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Amidines as amide bond replacements in VLA-4 antagonists. [electronic resource] by
- Kamenecka, Theodore M
- Park, You-Jung
- Lin, Linus S
- de Laszlo, Stephen
- McCauley, Ermengilda D
- Van Riper, Gail
- Egger, Linda
- Kidambi, Usha
- Mumford, Richard A
- Tong, Sharon
- Tang, Wei
- Colletti, Adria
- Teffera, Yohannes
- Stearns, Ralph
- MacCoss, Malcolm
- Schmidt, John A
- Hagmann, William K
Producer: 20041222
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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18.
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Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans. [electronic resource] by
- Singaraja, Roshni R
- Tietjen, Ian
- Hovingh, G Kees
- Franchini, Patrick L
- Radomski, Chris
- Wong, Kenny
- vanHeek, Margaret
- Stylianou, Ioannis M
- Lin, Linus
- Wang, Liangsu
- Mitnaul, Lyndon
- Hubbard, Brian
- Winther, Michael
- Mattice, Maryanne
- Legendre, Annick
- Sherrington, Robin
- Kastelein, John J
- Akinsanya, Karen
- Plump, Andrew
- Hayden, Michael R
Producer: 20180111
In:
Journal of lipid research vol. 55
Availability: No items available.
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19.
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Discovery of N-{N-[(3-cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(L)-prolyl}-4-[(3',5'-dichloroisonicotinoyl) amino]-(L)-phenylalanine (MK-0668), an extremely potent and orally active antagonist of very late antigen-4. [electronic resource] by
- Lin, Linus S
- Lanza, Thomas
- Jewell, James P
- Liu, Ping
- Jones, Carrie
- Kieczykowski, Gerard R
- Treonze, Kelly
- Si, Qian
- Manior, Salony
- Koo, Gloria
- Tong, Xinchun
- Wang, Junying
- Schuelke, Anne
- Pivnichny, James
- Wang, Regina
- Raab, Conrad
- Vincent, Stella
- Davies, Philip
- Maccoss, Malcolm
- Mumford, Richard A
- Hagmann, William K
Producer: 20090701
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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20.
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Alpha(4)beta(7)/alpha(4)beta(1) dual integrin antagonists block alpha(4)beta(7)-dependent adhesion under shear flow. [electronic resource] by
- Egger, Linda A
- Kidambi, Usha
- Cao, Jin
- Van Riper, Gail
- McCauley, Ermengilda
- Mumford, Richard A
- Amo, Suzanne
- Lingham, Russell
- Lanza, Thomas
- Lin, Linus S
- De Laszlo, Stephen E
- Young, David N
- Kopka, Ihor E
- Tong, Sharon
- Pikounis, Bill
- Benson, Evelyn
- Warwood, Sarah
- Bargatze, Robert F
- Hagmann, William K
- Schmidt, John A
- Detmers, Patricia A
Producer: 20020712
In:
The Journal of pharmacology and experimental therapeutics vol. 302
Availability: No items available.
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