Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction. [electronic resource]
Producer: 20200911ISSN:- 1946-6242
- Adult
- Aged
- Aged, 80 and over
- Aging -- pathology
- Albumins -- metabolism
- Animals
- Astrocytes -- drug effects
- Blood-Brain Barrier -- drug effects
- Chronic Disease
- Cognitive Dysfunction -- pathology
- Gene Knockdown Techniques
- Hippocampus -- drug effects
- Humans
- Mice, Transgenic
- Middle Aged
- Protein Kinase Inhibitors -- pharmacology
- Receptor, Transforming Growth Factor-beta Type I -- antagonists & inhibitors
- Signal Transduction
- Transforming Growth Factor beta -- metabolism
- Young Adult
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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