Mitochondrial targeting nanodrugs self-assembled from 9-O-octadecyl substituted berberine derivative for cancer treatment by inducing mitochondrial apoptosis pathways. [electronic resource]
Producer: 20200320Description: 27-42 p. digitalISSN:- 1873-4995
- A549 Cells
- Animals
- Antineoplastic Agents -- administration & dosage
- Apoptosis -- drug effects
- Berberine -- administration & dosage
- Cytochromes c -- metabolism
- Drug Delivery Systems
- Drug Liberation
- Female
- Humans
- Hyaluronic Acid -- administration & dosage
- Lung Neoplasms -- drug therapy
- Membrane Potential, Mitochondrial -- drug effects
- Mice, Inbred BALB C
- Mice, Nude
- Mitochondria -- drug effects
- Nanoparticles -- administration & dosage
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Reactive Oxygen Species -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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