2-(3-Methoxyphenyl)-5-methyl-1,8-naphthyridin-4(1H)-one (HKL-1) induces G2/M arrest and mitotic catastrophe in human leukemia HL-60 cells. [electronic resource]
Producer: 20120628Description: 219-26 p. digitalISSN:- 1096-0333
- Antineoplastic Agents -- pharmacology
- Aurora Kinase B
- Aurora Kinases
- CDC2 Protein Kinase -- antagonists & inhibitors
- Caspases -- metabolism
- Cell Cycle Checkpoints -- drug effects
- Cell Survival -- drug effects
- Chromosomal Proteins, Non-Histone -- antagonists & inhibitors
- Cyclin B1 -- antagonists & inhibitors
- Flow Cytometry
- HL-60 Cells
- Humans
- Inhibitory Concentration 50
- Leukemia -- drug therapy
- Microtubules -- metabolism
- Mitosis -- drug effects
- Naphthyridines -- pharmacology
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.