Design, Synthesis and Biological Evaluation of Novel N-hydroxyheptanamides Incorporating 6-hydroxy-2-methylquinazolin-4(3H)-ones as Histone Deacetylase Inhibitors and Cytotoxic Agents. [electronic resource]
Producer: 20200331Description: 1543-1557 p. digitalISSN:- 1875-5992
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Design
- Drug Screening Assays, Antitumor
- Hep G2 Cells
- Histone Deacetylase 2 -- antagonists & inhibitors
- Histone Deacetylase Inhibitors -- chemical synthesis
- Humans
- MCF-7 Cells
- Molecular Docking Simulation
- Molecular Structure
- Quinazolines -- chemistry
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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