High Uric Acid Activates the ROS-AMPK Pathway, Impairs CD68 Expression and Inhibits OxLDL-Induced Foam-Cell Formation in a Human Monocytic Cell Line, THP-1. [electronic resource]
Producer: 20170213Description: 538-548 p. digitalISSN:- 1421-9778
- AMP-Activated Protein Kinases -- metabolism
- ATP Binding Cassette Transporter, Subfamily G, Member 1 -- metabolism
- Acetylcysteine -- pharmacology
- Antigens, CD -- metabolism
- Antigens, Differentiation, Myelomonocytic -- metabolism
- Cell Differentiation -- drug effects
- Cell Line
- Cyclooxygenase 2 -- metabolism
- Foam Cells -- cytology
- Humans
- Lipoproteins, LDL -- pharmacology
- Models, Biological
- Monocytes -- cytology
- Oxidative Stress -- drug effects
- Phosphorylation -- drug effects
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Tetradecanoylphorbol Acetate -- pharmacology
- Time Factors
- Transcription Factor RelA -- metabolism
- Uric Acid -- pharmacology
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Publication Type: Journal Article
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