SIN1, a critical component of the mTOR-Rictor complex, is overexpressed and associated with AKT activation in medullary and aggressive papillary thyroid carcinomas. [electronic resource]
Producer: 20150218Description: 1542-8; discussion 1548-9 p. digitalISSN:- 1532-7361
- Adaptor Proteins, Signal Transducing -- genetics
- Adult
- Aged
- Biopsy, Needle
- Blotting, Western
- Carcinoma -- genetics
- Carcinoma, Neuroendocrine
- Carcinoma, Papillary
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Oncogene Protein v-akt -- genetics
- Sampling Studies
- Sensitivity and Specificity
- TOR Serine-Threonine Kinases -- genetics
- Thyroid Cancer, Papillary
- Thyroid Neoplasms -- genetics
- Transcriptional Activation
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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