Histone deacetylase inhibitor, Romidepsin (FK228) inhibits endometrial cancer cell growth through augmentation of p53-p21 pathway. [electronic resource]
Producer: 20170131Description: 161-6 p. digitalISSN:- 1950-6007
- Acetylation -- drug effects
- Apoptosis -- drug effects
- Caspases -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Depsipeptides -- pharmacology
- Dose-Response Relationship, Drug
- Endometrial Neoplasms -- enzymology
- Female
- G1 Phase -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Histone Deacetylase Inhibitors -- pharmacology
- Histones -- metabolism
- Humans
- Poly(ADP-ribose) Polymerases -- metabolism
- RNA, Messenger -- genetics
- Resting Phase, Cell Cycle -- drug effects
- Signal Transduction -- drug effects
- Time Factors
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article
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