Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. [electronic resource]
Producer: 20071227Description: 2908-22 p. digitalISSN:- 0890-9369
- Animals
- Cell Cycle Proteins -- metabolism
- Cell Line, Tumor
- Cell Nucleus -- metabolism
- Cells, Cultured
- Cullin Proteins -- metabolism
- Cyclin D1 -- genetics
- DNA -- genetics
- DNA Replication -- genetics
- DNA, Neoplasm -- genetics
- DNA-Binding Proteins -- metabolism
- HeLa Cells
- Humans
- Hydrolysis
- Lipopolysaccharides -- pharmacology
- Mice
- Mice, Transgenic
- Mutation
- NIH 3T3 Cells
- Osteosarcoma -- pathology
- S Phase
- Spleen -- cytology
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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