Regulation of hepatic glucose production and AMPK by AICAR but not by metformin depends on drug uptake through the equilibrative nucleoside transporter 1 (ENT1). [electronic resource]
Producer: 20190531Description: 2748-2758 p. digitalISSN:- 1463-1326
- AMP-Activated Protein Kinases -- metabolism
- Aminoimidazole Carboxamide -- analogs & derivatives
- Animals
- Biological Transport -- drug effects
- Equilibrative Nucleoside Transporter 1 -- drug effects
- Female
- Glucose -- metabolism
- Hepatocytes -- drug effects
- Hypoglycemic Agents -- pharmacokinetics
- Liver -- metabolism
- Metformin -- pharmacokinetics
- Mice
- Phosphorylation -- drug effects
- Ribonucleotides -- pharmacokinetics
- Signal Transduction -- drug effects
- Thioinosine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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