Oncogenic KRAS signaling activates mTORC1 through COUP-TFII-mediated lactate production. [electronic resource]
Producer: 20200505ISSN:- 1469-3178
- COUP Transcription Factor II -- genetics
- Cell Line, Tumor
- Gene Expression
- Gene Knockdown Techniques
- Glycolysis
- Humans
- Lactic Acid -- biosynthesis
- Mechanistic Target of Rapamycin Complex 1 -- metabolism
- Models, Biological
- Proto-Oncogene Proteins p21(ras) -- metabolism
- Ras Homolog Enriched in Brain Protein -- metabolism
- Signal Transduction
- Tuberous Sclerosis Complex 2 Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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