Results
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A randomised, double-blind, placebo-controlled trial of trametinib, an oral MEK inhibitor, in combination with gemcitabine for patients with untreated metastatic adenocarcinoma of the pancreas. [electronic resource] by
- Infante, Jeffrey R
- Somer, Bradley G
- Park, Joon Oh
- Li, Chung-Pin
- Scheulen, Max E
- Kasubhai, Saifuddin M
- Oh, Do-Youn
- Liu, Yuan
- Redhu, Suman
- Steplewski, Klaudia
- Le, Ngocdiep
Producer: 20140826
In:
European journal of cancer (Oxford, England : 1990) vol. 50
Availability: No items available.
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3.
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Phase 1 study of AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, in combination with chemotherapy in adults with advanced solid tumors. [electronic resource] by
- Mita, Alain C
- Takimoto, Chris H
- Mita, Monica
- Tolcher, Anthony
- Sankhala, Kamalesh
- Sarantopoulos, John
- Valdivieso, Manuel
- Wood, Leslie
- Rasmussen, Erik
- Sun, Yu-Nien
- Zhong, Z Don
- Bass, Michael B
- Le, NgocDiep
- LoRusso, Patricia
Producer: 20100812
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 16
Availability: No items available.
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4.
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Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors. [electronic resource] by
- Herbst, Roy S
- Hong, David
- Chap, Linnea
- Kurzrock, Razelle
- Jackson, Edward
- Silverman, Jeffrey M
- Rasmussen, Erik
- Sun, Yu-Nien
- Zhong, Don
- Hwang, Yuying C
- Evelhoch, Jeffrey L
- Oliner, Jonathan D
- Le, Ngocdiep
- Rosen, Lee S
Producer: 20090916
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 27
Availability: No items available.
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5.
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A phase 1b study of trametinib, an oral Mitogen-activated protein kinase kinase (MEK) inhibitor, in combination with gemcitabine in advanced solid tumours. [electronic resource] by
- Infante, Jeffrey R
- Papadopoulos, Kyriakos P
- Bendell, Johanna C
- Patnaik, Amita
- Burris, Howard A
- Rasco, Drew
- Jones, Suzanne F
- Smith, Lon
- Cox, Donna S
- Durante, Michael
- Bellew, Kevin M
- Park, Joohyun Jennifer
- Le, Ngocdiep T
- Tolcher, Anthony W
Producer: 20140409
In:
European journal of cancer (Oxford, England : 1990) vol. 49
Availability: No items available.
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6.
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A phase Ib dose-escalation study of the oral pan-PI3K inhibitor buparlisib (BKM120) in combination with the oral MEK1/2 inhibitor trametinib (GSK1120212) in patients with selected advanced solid tumors. [electronic resource] by
- Bedard, Philippe L
- Tabernero, Josep
- Janku, Filip
- Wainberg, Zev A
- Paz-Ares, Luis
- Vansteenkiste, Johan
- Van Cutsem, Eric
- Pérez-García, José
- Stathis, Anastasios
- Britten, Carolyn D
- Le, Ngocdiep
- Carter, Kirsten
- Demanse, David
- Csonka, Denes
- Peters, Malte
- Zubel, Angela
- Nauwelaerts, Heidi
- Sessa, Cristiana
Producer: 20151209
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 21
Availability: No items available.
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7.
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Safety, pharmacokinetic, pharmacodynamic, and efficacy data for the oral MEK inhibitor trametinib: a phase 1 dose-escalation trial. [electronic resource] by
- Infante, Jeffrey R
- Fecher, Leslie A
- Falchook, Gerald S
- Nallapareddy, Sujatha
- Gordon, Michael S
- Becerra, Carlos
- DeMarini, Douglas J
- Cox, Donna S
- Xu, Yanmei
- Morris, Shannon R
- Peddareddigari, Vijay G R
- Le, Ngocdiep T
- Hart, Lowell
- Bendell, Johanna C
- Eckhardt, Gail
- Kurzrock, Razelle
- Flaherty, Keith
- Burris, Howard A
- Messersmith, Wells A
Producer: 20121011
In:
The Lancet. Oncology vol. 13
Availability: No items available.
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8.
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Phase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor. [electronic resource] by
- Kim, Kevin B
- Kefford, Richard
- Pavlick, Anna C
- Infante, Jeffrey R
- Ribas, Antoni
- Sosman, Jeffrey A
- Fecher, Leslie A
- Millward, Michael
- McArthur, Grant A
- Hwu, Patrick
- Gonzalez, Rene
- Ott, Patrick A
- Long, Georgina V
- Gardner, Olivia S
- Ouellet, Daniele
- Xu, Yanmei
- DeMarini, Douglas J
- Le, Ngocdiep T
- Patel, Kiran
- Lewis, Karl D
Producer: 20130311
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 31
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9.
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Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial. [electronic resource] by
- Falchook, Gerald S
- Lewis, Karl D
- Infante, Jeffrey R
- Gordon, Michael S
- Vogelzang, Nicholas J
- DeMarini, Douglas J
- Sun, Peng
- Moy, Christopher
- Szabo, Stephen A
- Roadcap, Lori T
- Peddareddigari, Vijay G R
- Lebowitz, Peter F
- Le, Ngocdiep T
- Burris, Howard A
- Messersmith, Wells A
- O'Dwyer, Peter J
- Kim, Kevin B
- Flaherty, Keith
- Bendell, Johanna C
- Gonzalez, Rene
- Kurzrock, Razelle
- Fecher, Leslie A
Producer: 20121011
In:
The Lancet. Oncology vol. 13
Availability: No items available.
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10.
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DYNAMO: A Phase II Study of Duvelisib (IPI-145) in Patients With Refractory Indolent Non-Hodgkin Lymphoma. [electronic resource] by
- Flinn, Ian W
- Miller, Carole B
- Ardeshna, Kirit M
- Tetreault, Scott
- Assouline, Sarit E
- Mayer, Jiri
- Merli, Michele
- Lunin, Scott D
- Pettitt, Andrew R
- Nagy, Zoltan
- Tournilhac, Olivier
- Abou-Nassar, Karem-Etienne
- Crump, Michael
- Jacobsen, Eric D
- de Vos, Sven
- Kelly, Virginia M
- Shi, Weiliang
- Steelman, Lori
- Le, NgocDiep
- Weaver, David T
- Lustgarten, Stephanie
- Wagner-Johnston, Nina D
- Zinzani, Pier Luigi
Producer: 20200224
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 37
Availability: No items available.
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11.
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Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma. [electronic resource] by
- Long, Georgina V
- Stroyakovskiy, Daniil
- Gogas, Helen
- Levchenko, Evgeny
- de Braud, Filippo
- Larkin, James
- Garbe, Claus
- Jouary, Thomas
- Hauschild, Axel
- Grob, Jean Jacques
- Chiarion Sileni, Vanna
- Lebbe, Celeste
- Mandalà, Mario
- Millward, Michael
- Arance, Ana
- Bondarenko, Igor
- Haanen, John B A G
- Hansson, Johan
- Utikal, Jochen
- Ferraresi, Virginia
- Kovalenko, Nadezhda
- Mohr, Peter
- Probachai, Volodymyr
- Schadendorf, Dirk
- Nathan, Paul
- Robert, Caroline
- Ribas, Antoni
- DeMarini, Douglas J
- Irani, Jhangir G
- Casey, Michelle
- Ouellet, Daniele
- Martin, Anne-Marie
- Le, Ngocdiep
- Patel, Kiran
- Flaherty, Keith
Producer: 20141203
In:
The New England journal of medicine vol. 371
Availability: No items available.
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