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Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis. [electronic resource] by
- Layton, Mark E
- Reif, Alexander J
- Hartingh, Timothy J
- Rodzinak, Kevin
- Dudkin, Vadim
- Wang, Cheng
- Arrington, Ken
- Kelly, Michael J
- Garbaccio, Robert M
- O'Brien, Julie A
- Magliaro, Brian C
- Uslaner, Jason M
- Huszar, Sarah L
- Fillgrove, Kerry L
- Tang, Cuyue
- Kuo, Yuhsin
- Jacobson, Marlene A
Producer: 20160930
In:
Bioorganic & medicinal chemistry letters vol. 26
Availability: No items available.
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8.
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Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI. [electronic resource] by
- Pero, Joseph E
- Rossi, Michael A
- Kelly, Michael J
- Lehman, Hannah D G F
- Layton, Mark E
- Garbaccio, Robert M
- O'Brien, Julie A
- Magliaro, Brian C
- Uslaner, Jason M
- Huszar, Sarah L
- Fillgrove, Kerry L
- Tang, Cuyue
- Kuo, Yuhsin
- Joyce, Leo A
- Sherer, Edward C
- Jacobson, Marlene A
Producer: 20160317
In:
ACS medicinal chemistry letters vol. 7
Availability: No items available.
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9.
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3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts. [electronic resource] by
- Brnardic, Edward J
- Fraley, Mark E
- Garbaccio, Robert M
- Layton, Mark E
- Sanders, John M
- Culberson, Chris
- Jacobson, Marlene A
- Magliaro, Brian C
- Hutson, Pete H
- O'Brien, Julie A
- Huszar, Sarah L
- Uslaner, Jason M
- Fillgrove, Kerry L
- Tang, Cuyue
- Kuo, Yuhsin
- Sur, Sylvie M
- Hartman, George D
Producer: 20100802
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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Discovery of 3-substituted aminocyclopentanes as potent and orally bioavailable NR2B subtype-selective NMDA antagonists. [electronic resource] by
- Layton, Mark E
- Kelly, Michael J
- Rodzinak, Kevin J
- Sanderson, Philip E
- Young, Steven D
- Bednar, Rodney A
- Dilella, Anthony G
- McDonald, Terrence P
- Wang, Hao
- Mosser, Scott D
- Fay, John F
- Cunningham, Michael E
- Reiss, Duane R
- Fandozzi, Christine
- Trainor, Nicole
- Liang, Annie
- Lis, Edward V
- Seabrook, Guy R
- Urban, Mark O
- Yergey, James
- Koblan, Kenneth S
Producer: 20130411
In:
ACS chemical neuroscience vol. 2
Availability: No items available.
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11.
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Benzoxazolinone aryl sulfonamides as potent, selective Na [electronic resource] by
- Pero, Joseph E
- Rossi, Michael A
- Lehman, Hannah D G F
- Kelly, Michael J
- Mulhearn, James J
- Wolkenberg, Scott E
- Cato, Matthew J
- Clements, Michelle K
- Daley, Christopher J
- Filzen, Tracey
- Finger, Eleftheria N
- Gregan, Yun
- Henze, Darrell A
- Jovanovska, Aneta
- Klein, Rebecca
- Kraus, Richard L
- Li, Yuxing
- Liang, Annie
- Majercak, John M
- Panigel, Jacqueline
- Urban, Mark O
- Wang, Jixin
- Wang, Ying-Hong
- Houghton, Andrea K
- Layton, Mark E
Producer: 20170718
In:
Bioorganic & medicinal chemistry letters vol. 27
Availability: No items available.
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Discovery of selective, orally bioavailable, N-linked arylsulfonamide Na [electronic resource] by
- Roecker, Anthony J
- Egbertson, Melissa
- Jones, Kristen L G
- Gomez, Robert
- Kraus, Richard L
- Li, Yuxing
- Koser, Amy Jo
- Urban, Mark O
- Klein, Rebecca
- Clements, Michelle
- Panigel, Jacqueline
- Daley, Christopher
- Wang, Jixin
- Finger, Eleftheria N
- Majercak, John
- Santarelli, Vincent
- Gregan, Irene
- Cato, Matthew
- Filzen, Tracey
- Jovanovska, Aneta
- Wang, Ying-Hong
- Wang, Deping
- Joyce, Leo A
- Sherer, Edward C
- Peng, Xuanjia
- Wang, Xiu
- Sun, Haiyan
- Coleman, Paul J
- Houghton, Andrea K
- Layton, Mark E
Producer: 20170905
In:
Bioorganic & medicinal chemistry letters vol. 27
Availability: No items available.
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