Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia. [electronic resource]
Producer: 20170926Description: 892-906.e5 p. digitalISSN:- 2451-9448
- Acetylation -- drug effects
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors -- chemistry
- Cells, Cultured
- Epigenesis, Genetic
- Frontotemporal Dementia -- drug therapy
- Haploinsufficiency -- genetics
- Heterozygote
- Histone Deacetylase Inhibitors -- chemistry
- Histone Deacetylases -- chemistry
- Histones -- metabolism
- Humans
- Hydroxamic Acids -- chemistry
- Indoles -- chemistry
- Induced Pluripotent Stem Cells -- cytology
- Intercellular Signaling Peptides and Proteins -- genetics
- Light
- Neural Stem Cells -- cytology
- Progranulins
- Promoter Regions, Genetic
- Pyrimidines -- chemistry
- RNA Interference
- Up-Regulation -- drug effects
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Publication Type: Journal Article
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