Diverse heterocyclic scaffolds as allosteric inhibitors of AKT. [electronic resource]
Producer: 20120423Description: 1261-73 p. digitalISSN:- 1520-4804
- Allosteric Regulation
- Animals
- Biological Availability
- Biomarkers -- metabolism
- Cell Line, Tumor
- Drug Screening Assays, Antitumor
- Heterocyclic Compounds, 3-Ring -- chemical synthesis
- Heterocyclic Compounds, 4 or More Rings -- chemical synthesis
- Humans
- Imidazoles -- chemical synthesis
- Mice
- Mice, Nude
- Models, Molecular
- Neoplasm Transplantation
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Pyrazines -- chemical synthesis
- Pyrazoles -- chemical synthesis
- Pyridazines -- chemical synthesis
- Pyridines -- chemical synthesis
- Quinazolines -- chemical synthesis
- Rats
- Structure-Activity Relationship
- Transplantation, Heterologous
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Publication Type: Journal Article
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