Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression. [electronic resource]
Producer: 20071130Description: 263-73 p. digitalISSN:- 0301-472X
- Acetylation
- Acute Disease
- Apoptosis -- drug effects
- Cell Division -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinase Inhibitor p15 -- drug effects
- Cytidine -- analogs & derivatives
- DNA Methylation -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- G2 Phase -- drug effects
- Gene Expression Profiling
- HL-60 Cells
- Histones -- drug effects
- Humans
- Hydroxamic Acids -- pharmacology
- Leukemia, Myeloid -- drug therapy
- Phosphorylation
- Promoter Regions, Genetic -- drug effects
- Reverse Transcriptase Polymerase Chain Reaction -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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