Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model. [electronic resource]
Producer: 20180201Description: 721-734 p. digitalISSN:- 1538-7836
- Animals
- Antigen Presentation
- Blood Coagulation Tests
- CD4-Positive T-Lymphocytes -- cytology
- Disease Models, Animal
- Factor IX -- genetics
- Female
- Genetic Therapy -- methods
- Genetic Vectors
- Hemophilia B -- genetics
- Humans
- Immunoglobulin E -- immunology
- Immunoglobulin Fc Fragments -- immunology
- Immunoglobulin G -- immunology
- Male
- Mice
- Mice, Inbred C3H
- Receptors, IgG -- metabolism
- Recombinant Fusion Proteins -- immunology
- Surface Plasmon Resonance
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Research Support, U.S. Gov't, Non-P.H.S.
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