Results
|
|
1.
|
|
|
|
2.
|
|
|
|
3.
|
|
|
|
4.
|
Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition. [electronic resource] by
- LaRochelle, Jonathan R
- Fodor, Michelle
- Vemulapalli, Vidyasiri
- Mohseni, Morvarid
- Wang, Ping
- Stams, Travis
- LaMarche, Matthew J
- Chopra, Rajiv
- Acker, Michael G
- Blacklow, Stephen C
Producer: 20190422
In:
Nature communications vol. 9
Availability: No items available.
|
|
|
5.
|
Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR. [electronic resource] by
- Lu, Hengyu
- Liu, Chen
- Huynh, Hung
- Le, Thi Bich Uyen
- LaMarche, Matthew J
- Mohseni, Morvarid
- Engelman, Jeffrey A
- Hammerman, Peter S
- Caponigro, Giordano
- Hao, Huai-Xiang
Publication details: Oncotarget Jan 2020
In:
Oncotarget vol. 11
Availability: No items available.
|
|
|
6.
|
Synthesis of ciprofloxacin dimers for evaluation of bacterial permeability in atypical chemical space. [electronic resource] by
- Ross, Audrey G
- Benton, Bret M
- Chin, Donovan
- De Pascale, Gianfranco
- Fuller, John
- Leeds, Jennifer A
- Reck, Folkert
- Richie, Daryl L
- Vo, Jason
- LaMarche, Matthew J
Producer: 20160518
In:
Bioorganic & medicinal chemistry letters vol. 25
Availability: No items available.
|
|
|
7.
|
Antibiotic optimization and chemical structure stabilization of thiomuracin A. [electronic resource] by
- LaMarche, Matthew J
- Leeds, Jennifer A
- Dzink-Fox, Joanne
- Gangl, Eric
- Krastel, Philipp
- Neckermann, Georg
- Palestrant, Deborah
- Patane, Michael A
- Rann, Elin M
- Tiamfook, Stacey
- Yu, Donghui
Producer: 20121105
In:
Journal of medicinal chemistry vol. 55
Availability: No items available.
|
|
|
8.
|
4-Aminothiazolyl analogues of GE2270 A: antibacterial lead finding. [electronic resource] by
- LaMarche, Matthew J
- Leeds, Jennifer A
- Dzink-Fox, JoAnne
- Gunderson, Karl
- Krastel, Philipp
- Memmert, Klaus
- Patane, Michael A
- Rann, Elin M
- Schmitt, Esther
- Tiamfook, Stacey
- Wang, Bing
Producer: 20110606
In:
Journal of medicinal chemistry vol. 54
Availability: No items available.
|
|
|
9.
|
2-Alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication. [electronic resource] by
- Keaney, Erin P
- Connolly, Michael
- Dobler, Markus
- Karki, Rajeshri
- Honda, Ayako
- Sokup, Samantha
- Karur, Subramanian
- Britt, Shawn
- Patnaik, Anup
- Raman, Prakash
- Hamann, Lawrence G
- Wiedmann, Brigitte
- LaMarche, Matthew J
Producer: 20150306
In:
Bioorganic & medicinal chemistry letters vol. 24
Availability: No items available.
|
|
|
10.
|
Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2. [electronic resource] by
- LaRochelle, Jonathan R
- Fodor, Michelle
- Ellegast, Jana M
- Liu, Xiaoxi
- Vemulapalli, Vidyasiri
- Mohseni, Morvarid
- Stams, Travis
- Buhrlage, Sara J
- Stegmaier, Kimberly
- LaMarche, Matthew J
- Acker, Michael G
- Blacklow, Stephen C
Producer: 20171221
In:
Bioorganic & medicinal chemistry vol. 25
Availability: No items available.
|
|
|
11.
|
Design, synthesis, and evaluation of analogues of (+)-14-normethyldiscodermolide. [electronic resource] by
- Smith, Amos B
- Freeze, B Scott
- Lamarche, Matthew J
- Hirose, Tomoyasu
- Brouard, Ignacio
- Xian, Ming
- Sundermann, Kurt F
- Shaw, Simon J
- Burlingame, Mark A
- Horwitz, Susan Band
- Myles, David C
Producer: 20060705
In:
Organic letters vol. 7
Availability: No items available.
|
|
|
12.
|
Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues. [electronic resource] by
- Burlingame, Mark A
- Shaw, Simon J
- Sundermann, Kurt F
- Zhang, Dan
- Petryka, Joseph
- Mendoza, Esteban
- Liu, Fenghua
- Myles, David C
- LaMarche, Matthew J
- Hirose, Tomoyasu
- Scott Freeze, B
- Smith, Amos B
Producer: 20041222
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
|
|
|
13.
|
Structural and Functional Consequences of Three Cancer-Associated Mutations of the Oncogenic Phosphatase SHP2. [electronic resource] by
- LaRochelle, Jonathan R
- Fodor, Michelle
- Xu, Xiang
- Durzynska, Izabela
- Fan, Lixin
- Stams, Travis
- Chan, Ho Man
- LaMarche, Matthew J
- Chopra, Rajiv
- Wang, Ping
- Fortin, Pascal D
- Acker, Michael G
- Blacklow, Stephen C
Producer: 20160830
In:
Biochemistry vol. 55
Availability: No items available.
|
|
|
14.
|
Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide. [electronic resource] by
- Smith, Amos B
- Freeze, B Scott
- Lamarche, Matthew J
- Hirose, Tomoyasu
- Brouard, Ignacio
- Rucker, Paul V
- Xian, Ming
- Sundermann, Kurt F
- Shaw, Simon J
- Burlingame, Mark A
- Horwitz, Susan Band
- Myles, David C
Producer: 20060705
In:
Organic letters vol. 7
Availability: No items available.
|
|
|
15.
|
Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu. [electronic resource] by
- Morris, Rowan P
- Leeds, Jennifer A
- Naegeli, Hans Ulrich
- Oberer, Lukas
- Memmert, Klaus
- Weber, Eric
- LaMarche, Matthew J
- Parker, Christian N
- Burrer, Nathalie
- Esterow, Stacey
- Hein, Andreas E
- Schmitt, Esther K
- Krastel, Philipp
Producer: 20090630
In:
Journal of the American Chemical Society vol. 131
Availability: No items available.
|
|
|
16.
|
Identification and characterization of amino-piperidinequinolones and quinazolinones as MCHr1 antagonists. [electronic resource] by
- Blackburn, Christopher
- LaMarche, Matthew J
- Brown, James
- Che, Jennifer Lee
- Cullis, Courtney A
- Lai, Sujen
- Maguire, Martin
- Marsilje, Thomas
- Geddes, Bradley
- Govek, Elizabeth
- Kadambi, Vivek
- Doherty, Colleen
- Dayton, Brian
- Brodjian, Sevan
- Marsh, Kennan C
- Collins, Christine A
- Kym, Philip R
Producer: 20060809
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
|
|
|
17.
|
Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids. [electronic resource] by
- LaMarche, Matthew J
- Leeds, Jennifer A
- Amaral, Kerri
- Brewer, Jason T
- Bushell, Simon M
- Dewhurst, Janetta M
- Dzink-Fox, JoAnne
- Gangl, Eric
- Goldovitz, Julie
- Jain, Akash
- Mullin, Steve
- Neckermann, Georg
- Osborne, Colin
- Palestrant, Deborah
- Patane, Michael A
- Rann, Elin M
- Sachdeva, Meena
- Shao, Jian
- Tiamfook, Stacey
- Whitehead, Lewis
- Yu, Donghui
Producer: 20120305
In:
Journal of medicinal chemistry vol. 54
Availability: No items available.
|
|
|
18.
|
Antibacterial and Solubility Optimization of Thiomuracin A. [electronic resource] by
- LaMarche, Matthew J
- Leeds, Jennifer A
- Brewer, Jason
- Dean, Karl
- Ding, Jian
- Dzink-Fox, Joanne
- Gamber, Gabe
- Jain, Akash
- Kerrigan, Ryan
- Krastel, Philipp
- Lee, Kwangho
- Lombardo, Franco
- McKenney, David
- Neckermann, Georg
- Osborne, Colin
- Palestrant, Deborah
- Patane, Michael A
- Rann, Elin M
- Robinson, Zachary
- Schmitt, Esther
- Stams, Travis
- Tiamfook, Stacey
- Yu, Donghui
- Whitehead, Lewis
Producer: 20170609
In:
Journal of medicinal chemistry vol. 59
Availability: No items available.
|
|
|
19.
|
Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers. [electronic resource] by
- Hao, Huai-Xiang
- Wang, Hongyun
- Liu, Chen
- Kovats, Steven
- Velazquez, Roberto
- Lu, Hengyu
- Pant, Bhavesh
- Shirley, Matthew
- Meyer, Matthew J
- Pu, Minying
- Lim, Joanne
- Fleming, Michael
- Alexander, LeighAnn
- Farsidjani, Ali
- LaMarche, Matthew J
- Moody, Susan
- Silver, Serena J
- Caponigro, Giordano
- Stuart, Darrin D
- Abrams, Tinya J
- Hammerman, Peter S
- Williams, Juliet
- Engelman, Jeffrey A
- Goldoni, Silvia
- Mohseni, Morvarid
Producer: 20200707
In:
Molecular cancer therapeutics vol. 18
Availability: No items available.
|
|
|
20.
|
Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors. [electronic resource] by
- Bagdanoff, Jeffrey T
- Chen, Zhouliang
- Acker, Michael
- Chen, Ying-Nan
- Chan, Homan
- Dore, Michael
- Firestone, Brant
- Fodor, Michelle
- Fortanet, Jorge
- Hentemann, Murphy
- Kato, Mitsunori
- Koenig, Robert
- LaBonte, Laura R
- Liu, Shumei
- Mohseni, Movarid
- Ntaganda, Rukundo
- Sarver, Patrick
- Smith, Troy
- Sendzik, Martin
- Stams, Travis
- Spence, Stan
- Towler, Christopher
- Wang, Hongyun
- Wang, Ping
- Williams, Sarah L
- LaMarche, Matthew J
Producer: 20200303
In:
Journal of medicinal chemistry vol. 62
Availability: No items available.
|