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Discovery of Selective M4 Muscarinic Acetylcholine Receptor Agonists with Novel Carbamate Isosteres. [electronic resource] by
- Yang, Qingyi
- Lachapelle, Erik A
- Kablaoui, Natasha M
- Webb, Damien
- Popiolek, Michael
- Grimwood, Sarah
- Kozak, Rouba
- O'Connor, Rebecca E
- Lazzaro, John T
- Butler, Christopher R
- Zhang, Lei
Publication details: ACS medicinal chemistry letters Jun 2019
In:
ACS medicinal chemistry letters vol. 10
Availability: No items available.
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3.
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The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging. [electronic resource] by
- Zhang, Lei
- Chen, Laigao
- Beck, Elizabeth M
- Chappie, Thomas A
- Coelho, Richard V
- Doran, Shawn D
- Fan, Kuo-Hsien
- Helal, Christopher J
- Humphrey, John M
- Hughes, Zoe
- Kuszpit, Kyle
- Lachapelle, Erik A
- Lazzaro, John T
- Lee, Chewah
- Mather, Robert J
- Patel, Nandini C
- Skaddan, Marc B
- Sciabola, Simone
- Verhoest, Patrick R
- Young, Joseph M
- Zasadny, Kenneth
- Villalobos, Anabella
Producer: 20171121
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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Correction to Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor. [electronic resource] by
- Helal, Christopher J
- Arnold, Eric P
- Boyden, Tracey L
- Chang, Cheng
- Chappie, Thomas A
- Fennell, Kimberly F
- Forman, Michael D
- Hajos, Mihaly
- Harms, John F
- Hoffman, William E
- Humphrey, John M
- Kang, Zhijun
- Kleiman, Robin J
- Kormos, Bethany L
- LaChapelle, Erik A
- Lee, Che-Wah
- Lu, Jiemin
- Maklad, Noha
- McDowell, Laura
- Mente, Scot
- O'Connor, Rebecca E
- Pandit, Jayvardhan
- Piotrowski, Mary
- Schmidt, Anne W
- Schmidt, Christopher J
- Ueno, Hirokazu
- Verhoest, Patrick R
- Yang, Edward X
Publication details: Journal of medicinal chemistry 04 2018
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation. [electronic resource] by
- O'Neill, Brian T
- Beck, Elizabeth M
- Butler, Christopher R
- Nolan, Charles E
- Gonzales, Cathleen
- Zhang, Lei
- Doran, Shawn D
- Lapham, Kimberly
- Buzon, Leanne M
- Dutra, Jason K
- Barreiro, Gabriela
- Hou, Xinjun
- Martinez-Alsina, Luis A
- Rogers, Bruce N
- Villalobos, Anabella
- Murray, John C
- Ogilvie, Kevin
- LaChapelle, Erik A
- Chang, Cheng
- Lanyon, Lorraine F
- Steppan, Claire M
- Robshaw, Ashley
- Hales, Katherine
- Boucher, Germaine G
- Pandher, Karamjeet
- Houle, Christopher
- Ambroise, Claude W
- Karanian, David
- Riddell, David
- Bales, Kelly R
- Brodney, Michael A
Producer: 20190603
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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6.
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Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK). [electronic resource] by
- Huard, Kim
- Ahn, Kay
- Amor, Paul
- Beebe, David A
- Borzilleri, Kris A
- Chrunyk, Boris A
- Coffey, Steven B
- Cong, Yang
- Conn, Edward L
- Culp, Jeffrey S
- Dowling, Matthew S
- Gorgoglione, Matthew F
- Gutierrez, Jemy A
- Knafels, John D
- Lachapelle, Erik A
- Pandit, Jayvardhan
- Parris, Kevin D
- Perez, Sylvie
- Pfefferkorn, Jeffrey A
- Price, David A
- Raymer, Brian
- Ross, Trenton T
- Shavnya, Andre
- Smith, Aaron C
- Subashi, Timothy A
- Tesz, Gregory J
- Thuma, Benjamin A
- Tu, Meihua
- Weaver, John D
- Weng, Yan
- Withka, Jane M
- Xing, Gang
- Magee, Thomas V
Producer: 20171016
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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